Clinical Research Directory

Inclusion Criteria: 1. Age range: 20 to 80 years. 2. Patients must require tooth extraction (molars) as a result of caries, periodontal disease, tooth fracture or deemed unrestorable. 3. Non-infected sockets with intact buccal bone (≥1.5 mm in thickness measured through calipers) 4. Patients interested in implant placement following tooth extraction. Exclusion Criteria: 1. Allergies or hypersensitivities to study related medications. 2. Hematologic disorders/blood dyscrasias. 3. Active infectious diseases of any kind. 4. Liver or kidney dysfunction/failure. 5. Uncontrolled diabetes (HbA1c \> 8). 6. Active cancer treatment - such as active chemotherapy or radiation therapy. 7. Taking medications that will affect their bone healing (for example, bisphosphonates, Long-term NSAIDs use, Steroid). 8. Metabolic bone diseases that affect bone healing such as osteoporosis. 9. Pregnant or lactating women (self-reported). 10. Smoke 10 or more cigarettes per day (self-reported). 11. Poor oral hygiene. 12. Systemic diseases that compromise the immune system 13. Anti-coagulant therapy