Clinical Research Directory

Inclusion Criteria: * Group A: ex-athletes and continue to perform regular physical exercise (minimum 3 days/week of moderate-vigorous intensity). * Group B: sedentary individuals, (i.e., perform \<150 min of moderate intensity exercise per week or IPAQ score\<600 MET min/week). * In both groups (A and B) the conditions of physical exercise or sedentary lifestyle must have been maintained for at least 6 months prior to the evaluations. * Not having a history of neurological or psychiatric disorder or suffering from a serious medical condition Exclusion Criteria: * Medical conditions that have a high risk of associated cognitive symptoms. * Severe head injury with loss of consciousness within the previous 5 years. * Alcoholism (\>3 alcoholic drinks per day). * Chronic use of anxiolytics, neuroleptics, narcotics, anticonvulsants, or sedative hypnotics. * Hearing or visual impairment that would preclude testing * History of neurological disease with clinically relevant impact on cognition (e.g. cerebrovascular disease). * Incidental structural brain findings with impact on cognitive impairment or survival (e.g., malignant brain tumor). * Presence of severe systemic disease (e.g., cancer under treatment). * Consumption of anabolic substances. * Problems understanding spoken or written Spanish. * Those with pacemakers or metallic implants that may interfere with the MRI.