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Feasibility, Safety and Effectivity of an Exercise Intervention for Newly Diagnosed Multiple Myeloma Patients During Induction Therapy
Sponsor: University Hospital Heidelberg
Summary
Physical exercise is an important supportive therapy for cancer patients, which improves quality of life and can effectively counteract the side effects of drug therapy. There is very little experience whether physical activity can also be performed safely by patients with malignant diseases that affect bone stability. This applies in particular to patients with multiple myeloma, a disease characterized by a monoclonal proliferation of plasma cells in the bone marrow and often accompanied by severe bony destruction. Aim of this exploratory randomized controlled trial is to evaluate feasibility, safety and effectivity of an orthopaedic-guided exercise intervention during induction therapy in newly diagnosed multiple myeloma patients.
Official title: Investigation of an Exercise Intervention for Multiple Myeloma Patients With Stable and Unstable Osteolytic Lesions During Induction Therapy.
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2023-04-14
Completion Date
2026-06-27
Last Updated
2025-06-18
Healthy Volunteers
No
Conditions
Interventions
Exercise
Orthopedic consultation and home-based, individualized, structured resistance training during induction therapy.
Control group
Orthopedic consultation and stretching exercises/walking. No resistance training.
Locations (1)
Heidelberg University Hospital - GMMG Study Group
Heidelberg, Germany