Clinical Research Directory

Inclusion Criteria: * Healthy male or female subjects over 21 years of age seeking aesthetic improvement of the periorbital area * Subjects should be able to understand the investigative nature of the treatment, the possible benefits and side effects, and must sign the Informed Consent Form * Presence of clearly visible aging signs in the periorbital area (e.g. under-eye bags, periorbital wrinkles) when the face is relaxed as deemed appropriate by the Investigator * Subjects willing and able to abstain from partaking in any facial treatments other than the study procedure during study participation * Willingness to comply with study instructions, to return to the clinic for the required visits, and to have photographs of their face taken Exclusion Criteria: * Lower eyelid malposition (ectropion, entropion, retraction) * Blepharitis * Prior lower eyelid fat removal, skin resection, eyelid surgery or orbital trauma in the past 6 months, prior dermatochalasis of lower eyelids surgical treatment in the past 6 months * Filler injections in the treatment area and midface region within 3 months prior to the study participation * Neuromodulator treatment in the periorbital area within 3 months prior to the study participation * Tattoo(s) and/or permanent make-up in the intended treatment area * Prior usage within 30 days before the screening or planned usage during the study of retinol, or any medication that can cause dermal hypersensitivity * Bacterial or viral infection, acute inflammations * Impaired immune system * Isotretinoin in the past 12 months * Skin-related autoimmune diseases * Radiation therapy and chemotherapy * Poor healing and unhealed wounds in the treatment area * Metal implants near treatment area or neutral electrode * Permanent implant near the area to be treated * Pacemaker or internal defibrillator, or any other active electrical implant anywhere in the body * Current condition or history of skin cancer, or current condition of any other type of cancer, or pre-malignant moles * History of any type of malignant cancer * Active collagen diseases * Cardiovascular diseases (such as vascular diseases, peripheral arterial disease, thrombophlebitis and thrombosis) * Pregnancy/nursing or IVF procedure * History of bleeding coagulopathies, use of anticoagulants * Any active condition in the treatment area, such as sores, psoriasis, eczema, rash and rosacea * Any surgical procedure in the treatment area within the last three months or before complete healing * Poorly controlled endocrine disorders, such as diabetes * Electroanalgesia without exact diagnosis of pain etiology * Tuberculosis * Hepatitis * Febrile conditions * Acute neuralgia and neuropathy * Kidney or liver failure * Sensitive disorders in the treatment area * Varicose veins, pronounced edemas * Skin dermabrasion, skin resurfacing, or deep chemical peeling in the treatment area within 3 months prior to the treatment * Application in the area of chest, heart, carotid sinus, mouth (i.e. over the lips and in the near proximity) or over the eyes (i.e. over the eyeballs and eyelids) * Serious psychopathological disorders (such as schizophrenia) * Neurological disorders (such as multiple cerebrospinal sclerosis, epilepsy) * Blood vessels and lymphatic vessels inflammation * Scarring in the treatment area