Clinical Research Directory

Inclusion Criteria: 1. The patient's age from 18 years to 40 years old 2. Non -contributory medical history (ASA1) 3. Mature permanent posterior teeth with primary or secondary deep caries extending ≥ 2/3 of dentin 4. The tooth should give a positive response to cold testing 5. Clinical diagnosis of reversible pulpitis 6. The tooth is restorable via direct restoration, probing pocket depth and mobility are within normal limits 7. No signs of pulpal necrosis including sinus tract or swelling 8. No radiographic evidence of periapical changes indicative of apical periodontitis Exclusion Criteria: * Systemic medical conditions, pregnancy, alcoholic and smoker patients. 2- Teeth with spontaneous pain or percussion sensitivity in periodontal lesions, external or internal root resorption, sinus opening, mobility, or abscessed tooth. 3- Radiographic evidence of widened periodontal space, broken or interrupted lamina dura, and periapical radiolucency. 4- Intensified erosion damage or periodontitis. Patient reported clenching or bruxism, hopeless or non-restorable teeth. Immature teeth. 5- Patients with physical disabilities preventing tooth brushing. Patient had removable partial denture abutments, dental abscesses, pulp lesions, atypical facial pain, or pulpitis. 6- Patients had non-carious lesions like abrasion, erosion, attrition, or abfraction. 7- Patients with history of antibiotic or analgesics intake within few days of operative intervention. 8- Patients with previously root canal-treated teeth. 9- Periodontally compromised teeth. 10-Teeth that will be extracted for periodontal or orthodontic reasons as it will conduct for histological evaluation