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NOT YET RECRUITING
NCT07029100
NA

Feasibility of ORGAnoids in Routine Clinical Practice for Molecular Analysis of the GLIOvascular Niche in Patients With Primary Brain Tumors.

Sponsor: Centre Henri Becquerel

View on ClinicalTrials.gov

Summary

The main goal of ORGA-GLIO trial is to establish the feasibility in routine clinical practice of ex-vivo organoid cultures composed of tumor cells within their microenvironment (glioblastoma organoid - GBO) and intra- and peri-tumoral blood vessels (blood vessel organoid - BVO), derived from perioperative samples obtained during complete or partial surgical resection in patients with newly diagnosed glioblastoma.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2025-07-01

Completion Date

2029-07-01

Last Updated

2025-06-19

Healthy Volunteers

No

Conditions

Interventions

OTHER

Ex-vivo organoid culture

ex-vivo organoid cultures composed of tumor cells within their microenvironment (glioblastoma organoid - GBO) and intra- and peri-tumoral blood vessels (blood vessel organoid - BVO), derived from perioperative samples obtained during complete or partial surgical resection

Locations (3)

Groupe Hospitalier du Havre

Le Havre, France

Centre Henri Becquerel

Rouen, France

CHU Rouen

Rouen, France