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Association of Genetic Variants With Myopia
Sponsor: Beijing Visionly Plus Eye Hospital
Summary
This study aims to identify genetic factors linked to myopia, including those that influence a person's risk of developing it and how quickly it progresses (like changes in eye length). It will also examine how different treatments-such as low-dose atropine drops, orthokeratology lenses, specialized glasses, and increased outdoor time-interact with these genes. Finally, the research will develop a genetic risk score to help tailor personalized myopia prevention and treatment plans.
Official title: Genetic Variants and Their Association With Myopia Risk, Progression, and Optimal Interventions in Children
Key Details
Gender
All
Age Range
6 Years - 18 Years
Study Type
OBSERVATIONAL
Enrollment
1000
Start Date
2025-07-01
Completion Date
2028-12-31
Last Updated
2025-06-22
Healthy Volunteers
Yes
Conditions
Interventions
Oral swab DNA analyzed for myopia-related gene variants
Beyond detecting links between gene variants and myopia development, the testing analyzes how these variants influence treatment effectiveness. The aim is to enable early risk prediction and personalized treatment guidance for children through oral DNA testing.
Locations (2)
Beijing New Vision Eye Hospital
Beijing, China
Beijing Visionly Plus Eye Hospital
Beijing, China