Clinical Research Directory

Inclusion Criteria (patients): * Women aged 50 or over, with postmenopausal osteoporosis, fractured or not, diagnosed by their rheumatologist, * Able to give informed consent to participate in the research, * Affiliation with the French Social Security. Inclusion Criteria (healthy volunteers): * Women aged 50 or over, * Bone densitometry performed as part of the protocol, not suggestive of osteoporosis and validated by investigators, * Matched to patients by age, menopausal status, socio-educational level and manual laterality, * Able to give informed consent to participate in the research, * Affiliation with the French Social Security. * Registration or acceptance of registration in the national register of volunteers participating in Research. Exclusion Criteria (patient and healthy volunteers): * Presence of pacemaker, * Presence of medical devices (implants or prostheses), * Incompatibility of the patient with the safety criteria of the medical imaging center for carrying out magnetic resonance experiments at 3 Tesla, * Contraindications to the realization of MRI without injection such as claustrophobia proven, hearing aid, pacemaker wearers, wearing a brain clip, * Refusal to be informed in the event of the accidental discovery of an anomaly during the resting state functional magnetic resonance imaging, * Woman under legal protection or deprived of liberty, * Refusal to participation