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Implementing Depression and Adherence Treatment
Sponsor: University of Miami
Summary
The goal of this clinical trial is to compare a core set and enhanced set of implementation strategies in increasing the reach of evidence-based treatments to patients with HIV and depression. The main questions it aims to answer are: What proportion of patients start an evidence-based treatment for depression (reach)? What percentage of patients show clinical improvement in depression and what percentage attain viral undetectability within one year (effectiveness)? Researchers will compare high and low reach clinics to further inform tailored implementation strategies for uptake and maintenance. Clinics will be randomized into one of two study arms: core versus enhanced strategies. In both arms, core strategies will be utilized. Enhanced clinics will also receive more resource-intensive training.
Official title: Implementing Depression and Adherence Treatment in South Africa HIV Care
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
10
Start Date
2026-04-07
Completion Date
2030-05
Last Updated
2026-04-03
Healthy Volunteers
No
Conditions
Interventions
Core Implementation Strategies
* Task Sharing/Revise Professional Roles * Distribute educational materials/Dynamic Training/Address Stigma * Clinician Implementation Team Meetings * Partner with CoCT DoH * Champion * Audit and Feedback * Stage Scale Up/Tailoring
Enhanced Implementation Strategies
* Train the trainer * Ongoing supervision and consultation
Locations (3)
University of Miami
Miami, Florida, United States
Massachusetts General Hospital
Boston, Massachusetts, United States
University of Cape Town
Cape Town, South Africa