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RECRUITING
NCT07032363
NA

Implementing Depression and Adherence Treatment

Sponsor: University of Miami

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to compare a core set and enhanced set of implementation strategies in increasing the reach of evidence-based treatments to patients with HIV and depression. The main questions it aims to answer are: What proportion of patients start an evidence-based treatment for depression (reach)? What percentage of patients show clinical improvement in depression and what percentage attain viral undetectability within one year (effectiveness)? Researchers will compare high and low reach clinics to further inform tailored implementation strategies for uptake and maintenance. Clinics will be randomized into one of two study arms: core versus enhanced strategies. In both arms, core strategies will be utilized. Enhanced clinics will also receive more resource-intensive training.

Official title: Implementing Depression and Adherence Treatment in South Africa HIV Care

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

10

Start Date

2026-04-07

Completion Date

2030-05

Last Updated

2026-04-03

Healthy Volunteers

No

Interventions

OTHER

Core Implementation Strategies

* Task Sharing/Revise Professional Roles * Distribute educational materials/Dynamic Training/Address Stigma * Clinician Implementation Team Meetings * Partner with CoCT DoH * Champion * Audit and Feedback * Stage Scale Up/Tailoring

OTHER

Enhanced Implementation Strategies

* Train the trainer * Ongoing supervision and consultation

Locations (3)

University of Miami

Miami, Florida, United States

Massachusetts General Hospital

Boston, Massachusetts, United States

University of Cape Town

Cape Town, South Africa