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Imeroprubart in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Sponsor: Immunovant Sciences GmbH
Summary
This is a Phase 2b study to evaluate the efficacy and safety of Imeroprubart in adults with CIDP.
Official title: A Phase 2b, Multi-center, Randomized, Double-blind, Placebo-controlled Study of IMVT-1402 Treatment in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
162
Start Date
2025-03-18
Completion Date
2030-05
Last Updated
2026-05-13
Healthy Volunteers
No
Interventions
Imeroprubart
Dose 1 subcutaneous (SC) once weekly (QW) for 24 weeks (Period 1) and 52 weeks (Period 2)
Placebo
Matching placebo SC QW for 24 weeks (Period 1)
Locations (135)
Site Number - 1612
Tucson, Arizona, United States
Site Number - 1618
Carlsbad, California, United States
Site Number - 1619
Orange, California, United States
Site Number - 1607
Rancho Mirage, California, United States
Site Number -1608
San Francisco, California, United States
Site Number - 1626
Parker, Colorado, United States
Site Number - 1621
New Haven, Connecticut, United States
Site Number - 1630
Washington D.C., District of Columbia, United States
Site Number - 1601
Washington D.C., District of Columbia, United States
Site Number - 1603
Maitland, Florida, United States
Site Number - 1606
Miami, Florida, United States
Site Number - 1617
Ormond Beach, Florida, United States
Site Number - 1620
Port Charlotte, Florida, United States
Site Number - 1633
Rockledge, Florida, United States
Site Number - 1602
Kansas City, Kansas, United States
Site Number - 1611
Nicholasville, Kentucky, United States
Site Number - 1623
Boston, Massachusetts, United States
Site Number - 1625
Worcester, Massachusetts, United States
Site Number - 1629
Detroit, Michigan, United States
Site Number - 1634
Las Vegas, Nevada, United States
Site Number - 1605
New York, New York, United States
Site Number - 1627
New York, New York, United States
Site Number - 1635
Chapel Hill, North Carolina, United States
Site Number - 1610
Charlotte, North Carolina, United States
Site Number - 1624
Canton, Ohio, United States
Site Number - 1631
Yukon, Oklahoma, United States
Site Number - 1614
Portland, Oregon, United States
Site Number - 1616
Philadelphia, Pennsylvania, United States
Site Number - 1622
Houston, Texas, United States
Site Number - 1628
San Antonio, Texas, United States
Site Number - 1613
Milwaukee, Wisconsin, United States
Site Number - 5002
Buenos Aires, Argentina
Site Number - 5001
Córdoba, Argentina
Site Number - 5003
Córdoba, Argentina
Site Number - 5000
Rosario, Argentina
Site Number - 5100
Macquarie Park, Australia
Site Number - 5103
Parkville, Australia
Site Number - 5102
Woolloongabba, Australia
Site Number - 5200
Vienna, Austria
Site Number - 5300
Leuven, Belgium
Site Number - 5400
Banja Luka, Bosnia and Herzegovina
Site Number - 5402
Bihać, Bosnia and Herzegovina
Site Number - 5401
Mostar, Bosnia and Herzegovina
Site Number - 5403
Sarajevo, Bosnia and Herzegovina
Site Number - 5506
Brasília, Brazil
Site Number - 5503
Campinas, Brazil
Site Number - 5500
Curitiba, Brazil
Site Number - 5502
Joinville, Brazil
Site Number - 5501
Porto Alegre, Brazil
Site Number - 5504
Porto Alegre, Brazil
Site Number - 5505
Vila Clementino, Brazil
Site Number - 5601
Pleven, Bulgaria
Site Number - 5600
Sofia, Bulgaria
Site Number - 5602
Sofia, Bulgaria
Site Number - 5603
Sofia, Bulgaria
Site Number - 5604
Sofia, Bulgaria
Site Number - 5800
Bogotá, Colombia
Site Number - 3600
Copenhagen, Denmark
Site Number - 3601
Odense, Denmark
Site Number - 7251
Tallinn, Estonia
Site Number - 3800
Turku, Finland
Site Number - 6505
Berlin, Germany
Site Number - 6501
Bochum, Germany
Site Number - 6504
Essen, Germany
Site Number - 6500
Tübingen, Germany
Site Number - 6503
Ulm, Germany
Site Number - 6502
Würzburg, Germany
Site Number - 3901
Alexandroupoli, Greece
Site Number - 3902
Athens, Greece
Site Number - 3905
Chaïdári, Greece
Site Number - 3906
Heraklion, Greece
Site Number - 3903
Ioannina, Greece
Site Number - 3904
Larissa, Greece
Site Number - 3900
Pátrai, Greece
Site Number - 7551
Budapest, Hungary
Site Number - 7550
Kistarcsa, Hungary
Site Number - 7552
Pécs, Hungary
Site Number - 4100
Waterford, Ireland
Site Number - 6004
Bergamo, Italy
Site Number - 6007
Bologna, Italy
Site Number - 6000
Brescia, Italy
Site Number - 6009
Milan, Italy
Site Number - 6001
Milan, Italy
Site Number -6005
Milan, Italy
Site Number - 6011
Pavia, Italy
Site Number - 6010
Pisa, Italy
Site Number - 6002
Roma, Italy
Site Number - 6006
Roma, Italy
Site Number - 6003
Siena, Italy
Site Number - 2603
Colonia del Valle, Mexico
Site Number - 2600
Culiacán, Mexico
Site Number - 2602
Tlalpan, Mexico
Site Number - 2601
Veracruz, Mexico
Site Number - 2200
Utrecht, Netherlands
Site Number - 2300
Oslo, Norway
Site Number - 2401
Callao, Peru
Site Number - 2400
Lima, Peru
Site Number - 3007
Bydgoszcz, Poland
Site Number - 3008
Gdansk, Poland
Site Number - 3004
Katowice, Poland
Site Number - 3000
Krakow, Poland
Site Number - 3003
Krakow, Poland
Site Number - 3001
Lublin, Poland
Site Number - 3005
Lublin, Poland
Site Number - 3002
Poznan, Poland
Site Number - 3006
Warsaw, Poland
Site Number -2902
Almada, Portugal
Site Number - 2901
Matosinhos Municipality, Portugal
Site Number - 2903
Vila Nova de Gaia, Portugal
Site Number - 7503
Bucharest, Romania
Site Number - 7500
Constanța, Romania
Site Number - 9000
Belgrade, Serbia
Site Number - 9003
Belgrade, Serbia
Site Number -9002
Kragujevac, Serbia
Site Number - 9001
Niš, Serbia
Site Number - 2800
Martin, Slovakia
Site Number - 2802
Prešov, Slovakia
Site Number - 2801
Rimavská Sobota, Slovakia
Site Number - 7351
Ljubljana, Slovenia
Site Number - 7100
Barcelona, Spain
Site Number - 7101
Barcelona, Spain
Site Number - 7104
Bilbao, Spain
Site Number - 7103
Córdoba, Spain
Site Number - 7102
Santiago de Compostela, Spain
Site Number - 7105
Valencia, Spain
Site Number - 4250
Bakırköy, Turkey (Türkiye)
Site Number - 4253
Başakşehir, Turkey (Türkiye)
Site Number - 4255
Bursa, Turkey (Türkiye)
Site Number - 4251
Istanbul, Turkey (Türkiye)
Site Number - 4254
Izmir, Turkey (Türkiye)
Site Number - 4252
Samsun, Turkey (Türkiye)
Site Number - 7001
Bristol, United Kingdom
Site Number - 7002
Glasgow, United Kingdom
Site Number - 7000
Salford, United Kingdom
Site Number - 7003
Southampton, United Kingdom