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Therapeutic Effect of Oral Hyaluronic Acid on Knee Osteoarthritis
Sponsor: Taichung Veterans General Hospital
Summary
The goal of this clinical trial is to investigate the effect of oral hyaluronate in patients with knee osteoarthritis. The main question it aims to answer is: the therapeutic effect in the combined treatment of oral nutritional supplement based on hyaluronic acid with hyaluronic acid intra-articular Injection on symptomatic knee osteoarthritis. Researchers will compare it to those who receive only hyaluronic acid injection to see if the combined treatment is better. Participants will receive a total of three months of oral hyaluronate or placebo agents.
Official title: Therapeutic Effect of Combined Treatment of Oral Nutritional Supplement Based on Hyaluronic Acid With Hyaluronic Acid Intra-articular Injection on Symptomatic Knee Osteoarthritis
Key Details
Gender
All
Age Range
60 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2023-04-21
Completion Date
2025-08
Last Updated
2025-06-24
Healthy Volunteers
No
Conditions
Interventions
oral hyaluronate and injection
The patient receives oral hyaluronate and hyaluronate injection
hyaluronate injection
The patient receives hyaluronate injection only
Locations (1)
Taichung Veterans General Hospital
Taichung, Taiwan, Taiwan