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ENROLLING BY INVITATION
NCT07033325

University-Based Chagas Testing in Salta Province, Argentina

Sponsor: Mundo Sano Foundation

View on ClinicalTrials.gov

Summary

The goal of this observational study is to improve access to diagnosis and treatment for chronic Trypanosoma cruzi infection among university students of all ages and genders at the National University of Salta (UNSa), Argentina. The main questions it aims to answer are: * What is the seroprevalence and geographic distribution of T. cruzi infection in UNSa students? * Can voluntary point-of-care tests performed at university serve as an effective opportunity for timely diagnosis and linkage to care for Chagas disease? Participants will: 1. Be offered a RDTs (WL Check Chagas, Wiener Lab) during their regular activities in the university. 2. If RDT is positive, be referred to the health system for confirmatory testing and treatment. 3. Receive follow-up support by trained staff via phone. A subgroup of RDT-negative students will have serum samples preserved and analyzed later via ELISA to verify RDT accuracy.

Official title: Mass Screening for Chagas Disease Among University Entrants as a Strategy to Improve Access to Diagnosis and Treatment in the Province of Salta, Argentina

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

5000

Start Date

2024-09-11

Completion Date

2026-02-01

Last Updated

2025-06-24

Healthy Volunteers

Yes

Interventions

DIAGNOSTIC_TEST

Rapid diagnostic test (RDT) for Trypanosoma cruzi infection.

Rapid diagnostic tests (RDTs) for the detection of Trypanosoma cruzi infection are performed in university facilities, outside of a clinical care setting, using a point-of-care approach. The study population includes adult male and female participants from the university community. This intervention differs from most existing strategies that target exclusively women of reproductive age and/or newborns to control vertical transmission; instead, it focuses on broader population-based screening and linkage to care for chronic infections.

Locations (2)

Universidad Nacional de Salta

Orán, Salta Province, Argentina

Universidad Nacional de Salta

Salta, Argentina