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RECRUITING
NCT07033858
NA

Evaluaion the Short Term Effects of Advograf Plus Rapamiune After Kidney Transplantation

Sponsor: Shahid Beheshti University of Medical Sciences

View on ClinicalTrials.gov

Summary

Cornerstone immunosuppressive therapy currently relies on immediate-release tacrolimus, a calcineurin inhibitor (CNI) that is potentially nephrotoxic and is more diabetogenic than cyclosporine A. A new formulation of tacrolimus has been launched: an extended-release formulation (Advagraf®/Astagraf XL®, Astellas company).

Official title: Investigating the Effect of Low-dose Extended-release Tacrolimus and Sirolimus on the Short-term Outcomes of Allograft Kidney Transplantation

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

50

Start Date

2025-03-01

Completion Date

2026-07-01

Last Updated

2025-06-24

Healthy Volunteers

No

Interventions

DRUG

Rapamune Pill

Rapamiune Tablet 1mg daily plus Advograf plus prednisolone

Locations (1)

Nooshin Dalili

Tehran, Iran