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Effects of Negative Pressure Ventilation Onto Hemodynamics and Right Ventricular Funktion in Patients After Implantation of a Left Ventricular Assist Device.
Sponsor: Karlsburg Hospital
Summary
All patients undergoing an implantation of a durable left ventricular assist device and monitored by pulmonary artery catheter showing no adverse events after surgery are included in the study and ventilated for 15 minutes using extra thoracic negative pressure ventilation and usual intrathoracic positive pressure ventilation. Hemodynamics changes between both ventilation modes, especially focussing on right ventricular function and measured by a pulmonary artery catheter, are compared.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2025-10-01
Completion Date
2026-12-01
Last Updated
2026-02-18
Healthy Volunteers
No
Conditions
Interventions
Negative pressure ventilation
All participants are ventilated with negative pressure ventilation first
positive pressure ventilation
All participants are ventilated using positive pressure ventilation after negative pressure ventilation
Locations (1)
Klinikum Karlsburg
Karlsburg, Germany