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Transcranial Magnetic Stimulation for Chronic Scrotal Content Pain
Sponsor: Medical University of South Carolina
Summary
The purpose of this study is to perform an open label feasibility trial of TMS for the treatment of chronic scrotal content pain.
Key Details
Gender
MALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2026-04-30
Completion Date
2030-04-01
Last Updated
2026-04-07
Healthy Volunteers
No
Conditions
Interventions
Transcranial magnetic stimulation
Resting motor threshold will be established by first finding the area of the motor cortex associated with visible twitch of the right abductor pollicis brevis (APB). Parameter Estimation by Sequential Testing (PEST) will be conducted to quantify resting motor threshold using visible APB twitch. The left dorsolateral prefrontal cortex (DLPFC) will be located using the Beam F3 method and marked with a felt-tipped marker on the scalp. TMS will be delivered over left DLPFC at 110% of resting motor threshold at 10Hz (5-seconds-on; 10-seconds-off) for 15 minutes per session (3000 pulses), 3 sessions each day (30-minute rest in-between sessions), for 3 days (within 5 consecutive days; a total of 27,000 pulses).
Locations (1)
Medical University of South Carolina
Charleston, South Carolina, United States