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COMPLETED
NCT07035301
NA

Application of Low-dose Muscle Relaxants in Bronchoscopic Interventional Procedures

Sponsor: Harbin Medical University

View on ClinicalTrials.gov

Summary

The purpose of this clinical trial is to observe the use of low-dose muscle relaxants in bronchoscopy intervention surgeries, compared with no muscle relaxants, in terms of the satisfaction of tracheal tube insertion after anesthesia induction, the incidence of laryngospasm, the grading of intraoperative cough and movement, and the recovery of patients after surgery. The main questions it aims to answer are: * How safe and feasible is the use of low-dose muscle relaxants in bronchoscopy intervention surgeries? * Is the muscle relaxant regimen better than the no-muscle-relaxant regimen? Participants will: * During anesthesia induction, the experimental group will use low-dose muscle relaxants for anesthesia, while the control group will not use muscle relaxants for anesthesia. * Record the satisfaction of mask ventilation and the incidence of laryngospasm.

Official title: Effects of Low-Dose Neuromuscular Blocking Agents on Perioperative Complications During Bronchoscopic Procedures

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

153

Start Date

2025-03-14

Completion Date

2026-10-14

Last Updated

2026-10-19

Healthy Volunteers

No

Interventions

DRUG

Normal Saline (Placebo)

During anesthesia induction, an equal volume of normal saline was used instead of rocuronium for anesthesia.

DRUG

Lidocaine Intravenous Infusion

Lidocaine was administered at a dose of 0.5mg/kg for the induction of anesthesia.

DRUG

Remimazolam Tosilate

Remimazolam was administered at a dose of 0.2 mg/kg for the induction of anesthesia.

DRUG

Remifentanil

Remifentanil was administered at a dose of 3 micrograms per kilogram for the induction of anesthesia.

DRUG

Rocuronium (0.15mg/kg/body mass)

Rocuronium was administered at a dose of 0.15mg/kg for the induction of anesthesia.

Locations (1)

The First Affiliated Hospital of Harbin Medical University

Harbin, Heilongjiang, China