Clinical Research Directory

Inclusion Criteria: 1. Patient age between 18 and 80 years old, male or non-pregnant female. 2. Confirmed diagnosis of paroxysmal atrial fibrillation requiring cryoablation surgery. 3. Fully understands the treatment plan and voluntarily signs the informed consent form, willing to undergo the examinations, surgery, and follow-up required by the plan. Exclusion Criteria: 1. Patients who have undergone atrial fibrillation ablation surgery 2. Reproductive-age patients who cannot use effective contraception within 12 months of enrolment 3. Left atrial size ≥50 mm, left ventricular ejection fraction ≤40% 4. Left atrial thrombus 5. Patients who have undergone atrial septal defect repair surgery or atrial myxoma 6. Patients with cerebrovascular disease within the past 3 months (including stroke or transient ischaemic attack) 7. Patients with cardiovascular events within the past 3 months (including acute myocardial infarction, coronary artery intervention or bypass surgery, artificial valve replacement or repair, or atrial or ventricular incision) 8. Patients with acute or severe systemic infection 9. Patients with severe liver or kidney disease 10. Patients with a significant tendency to bleed or haematological disorders 11. Patients with malignant tumours or end-stage diseases 12. Patients deemed ineligible for this trial by the investigator