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ENROLLING BY INVITATION
NCT07036302
NA

Comparative Effects Of Trichloroacetic Chemical Peel And Fractional Laser

Sponsor: Jose Roberto Cortelli

View on ClinicalTrials.gov

Summary

More than aesthetics, the search for orofacial harmonization treatments has increased when the negative emotional impact of some facial conditions such as melasma and acne scars is recognized. This study will evaluate the effects of chemical peels with 35% TCA (trichloroacetic acid) and two types of fractional laser in orofacial harmonization procedures. A sample of 100-120 participants at least 18 years of age, male or female, with complaints of melasma (n=36 to 40), acne scars (n=36 to 40) or facial wrinkles (n=36 to 40) will be recruited to underwent 3 consecutive treatment sections every 30 days. Besides clinical improvements, global satisfaction scale of the professional and the patient will be measured in addition to the impact of the treatment on the quality of life of the participants and the sensory experience in relation to pain. Pre- and pos-peeling home care will be provided to measure whether they influence results or not. The aim of this study is to identify the most appropriate treatment strategy for frequent complaints in clinical practice, and among them, the one that promotes the best experience, with the shortest recovery time and is cost-effective.

Official title: Clinical Evaluation of Trichloroacetic Chemical Peel And Fractional Laser: Comparative Analysis Of Quantitative And Qualitative Parameters

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

120

Start Date

2025-06-02

Completion Date

2026-12

Last Updated

2025-06-25

Healthy Volunteers

No

Interventions

PROCEDURE

35% TCA combined with croton oil peel

3 sections every 30 days of 35% TCA combined with croton oil peel

PROCEDURE

Isolate 35% TCA peel

3 sections every 30 days of isolate 35% TCA peel

RADIATION

Erbium-YAG laser

3 sections every 30 days of Er-YAG laser

RADIATION

Neodymium -YAG laser Q-switched

3 sections every 30 days of ND-YAG laser

Locations (2)

Cavalca & Cortelli Research Center

Taubaté, São Paulo, Brazil

University of Taubate Dental School

Taubaté, São Paulo, Brazil