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Comparative Effects Of Trichloroacetic Chemical Peel And Fractional Laser
Sponsor: Jose Roberto Cortelli
Summary
More than aesthetics, the search for orofacial harmonization treatments has increased when the negative emotional impact of some facial conditions such as melasma and acne scars is recognized. This study will evaluate the effects of chemical peels with 35% TCA (trichloroacetic acid) and two types of fractional laser in orofacial harmonization procedures. A sample of 100-120 participants at least 18 years of age, male or female, with complaints of melasma (n=36 to 40), acne scars (n=36 to 40) or facial wrinkles (n=36 to 40) will be recruited to underwent 3 consecutive treatment sections every 30 days. Besides clinical improvements, global satisfaction scale of the professional and the patient will be measured in addition to the impact of the treatment on the quality of life of the participants and the sensory experience in relation to pain. Pre- and pos-peeling home care will be provided to measure whether they influence results or not. The aim of this study is to identify the most appropriate treatment strategy for frequent complaints in clinical practice, and among them, the one that promotes the best experience, with the shortest recovery time and is cost-effective.
Official title: Clinical Evaluation of Trichloroacetic Chemical Peel And Fractional Laser: Comparative Analysis Of Quantitative And Qualitative Parameters
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2025-06-02
Completion Date
2026-12
Last Updated
2025-06-25
Healthy Volunteers
No
Interventions
35% TCA combined with croton oil peel
3 sections every 30 days of 35% TCA combined with croton oil peel
Isolate 35% TCA peel
3 sections every 30 days of isolate 35% TCA peel
Erbium-YAG laser
3 sections every 30 days of Er-YAG laser
Neodymium -YAG laser Q-switched
3 sections every 30 days of ND-YAG laser
Locations (2)
Cavalca & Cortelli Research Center
Taubaté, São Paulo, Brazil
University of Taubate Dental School
Taubaté, São Paulo, Brazil