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Effects of Salbutamol in Athletes and Implications for Screening and Sports
Sponsor: University of British Columbia
Summary
β2-Agonists, commonly used to treat asthma, have also been used by athletes to enhance performance, leading to their ban by the International Olympic Committee in 1972. Research has shown non-asthmatics receive no benefit from these drugs at therapeutic dosages; however, many elite athletes still use them, and asthmatic athletes often win more Olympic medals. In some non-asthmatics, β2-agonists may improve breathing limitations during high intensity exercise, which may improve performance. Therefore, we aim to examine if there is a select group of non-asthmatic individuals who experience breathing limitations that may receive benefit from β2-agonists.
Official title: Physiological, Sensory and Ergogenic Effects of Salbutamol - Implications for Athletic Screening and β2 Agonist Use in Sport
Key Details
Gender
All
Age Range
18 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
64
Start Date
2025-10-30
Completion Date
2030-12-31
Last Updated
2026-03-13
Healthy Volunteers
Yes
Conditions
Interventions
Salbutamol
Meter-dose inhaler of salbutamol performed using large-volume spacer
Placebo
Meter-dose inhaler of placebo performed using large-volume spacer
Locations (1)
St. Paul's Hospital
Vancouver, British Columbia, Canada