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EVOLUTION OF D-DIMER AS A MARKER OF BLEEDING RISK ON ECMO
Sponsor: University Hospital, Strasbourg, France
Summary
ECMO (extracorporeal membrane oxygenation) is a life-saving device, used in intensive care to treat severe respiratory or cardiac failure. However, it carries a high risk of serious life-threatening bleeding. Bleeding complications have been attributed to coagulopathy triggered either by the underlying pathology or by the extracorporeal circuit itself, as well as excessive or inappropriate anticoagulation initiated to prevent thrombotic complications. The objective of this cohort is to confirm the interest of the evolution of D-dimers as a prognostic marker of serious bleeding events in patients on veno-venous (VV) or veno-arterial (VA) ECMO, and to determine the threshold.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2025-11-27
Completion Date
2027-06-01
Last Updated
2025-12-01
Healthy Volunteers
No
Interventions
Blood sampling collection
Collection of an additional of 2.7mL citrate tube of blood for a D-dimer dosage.
Locations (1)
Service de Médecine Intensive - Réanimation Nouvel Hôpital Civil
Strasbourg, France