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Confocal Laser Endomicroscopy Assisted Ultrasound Guided Pleural Biopsy
Sponsor: China-Japan Friendship Hospital
Summary
This study aimed to evaluate the diagnostic yield and safety of confocal laser endomicroscopy and ultrasound-guided pleural biopsy in diagnosing patients with unknown pleural effusion.
Official title: Diagnostic Yield and Safety of Probe-based COnfocaL LAser Endomicroscopy and Ultrasound-guided Pleural BiOpsy in Diagnosing Patients With Unknown pleuRAl Effusion: a Protocol of a Multicenter, Randomized cONtrolled Trial (COLLABORATION-Ⅱ）
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
260
Start Date
2025-07-01
Completion Date
2027-07-01
Last Updated
2025-06-27
Healthy Volunteers
No
Conditions
Interventions
Confocoal laser endomicroscopy-assisted ultrasound-guided pleural biopsy
Using the probe-based confocal laser endomicroscopy to detect the pleural, and ensure the biopsy location. Then, use the pleural biopsy tool to complete the pleural biopsy. The whole procession will under the ultrasound guidance.
Ultrasound-guided pleural biopsy
Using ultrasound to detect the biopsy site and perform pleural biopsy.