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A Trial of Varenicline for E-cigarette Cessation
Sponsor: Yale University
Summary
This is randomized, placebo-controlled clinical trial in treatment-seeking adults who report regular e-cigarette use to test the hypothesis that varenicline is efficacious for quitting e-cigarettes.
Official title: Investigating Efficacious E-Cigarette Interventions and Cessation Effects on Cancer-Related Biomarkers: A Randomized Trial of Varenicline in Adults
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
326
Start Date
2025-10-14
Completion Date
2030-10-30
Last Updated
2025-12-17
Healthy Volunteers
No
Conditions
Interventions
Varenicline 1mg BID
12 weeks following the standard titration of 1 mg, twice daily
Placebo
Matching placebo twice daily
Locations (2)
Yale Cancer Center/Smilow Cancer Hospital at Yale-New Haven
New Haven, Connecticut, United States
Hollings Cancer Center at MUSC (HCC)
Charleston, South Carolina, United States