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ACTIVE NOT RECRUITING
NCT07040969
PHASE2

Spirulina-Derived Product Alleviates Oral Mucositis in Patients Undergoing Radiotherapy for Malignant Head and Neck Tumors

Sponsor: West China Hospital

View on ClinicalTrials.gov

Summary

To evaluate the efficacy and safety of Spirulina-Derived Product for prevention and treatment of oral mucositis in patients undergoing radiotherapy for malignant head and neck tumors.

Official title: Spirulina-Derived Product Alleviates Oral Mucositis in Patients Undergoing Radiotherapy for Malignant Head and Neck Tumors: A Randomized Controlled Trial

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

70

Start Date

2025-06-27

Completion Date

2026-04-30

Last Updated

2026-04-07

Healthy Volunteers

No

Interventions

DRUG

Spray of spirulina derivatives

An oral spray formulated with purified spirulina-derived exosomes.

DRUG

Spray of placebo

The placebo oral spray will be formulated with inactive ingredients matched in appearance and flavor profile to the active spirulina-derived product.

RADIATION

Radiotherapy

One of the inclusion criteria for the study was that patients with squamous carcinoma of the head and neck (including nasopharyngeal carcinoma) needed to receive either radiotherapy alone or simultaneous radiotherapy and chemotherapy.

Locations (1)

West China Hospital, Sichuan University

Chengdu, Sichuan, China