Clinical Research Directory

Inclusion Criteria: * Age 18 -100 * Capacity to provide Informed Consent * Unilateral above or below knee amputation more than 3 months prior to enrollment * Absence of cognitive impairment, operationally defined as a Montreal Cognitive Assessment score of 18 or greater1. * Pain averaged over the preceding 1 month in the phantom limb rated as greater than 4 on a scale of 0-10. Exclusion Criteria: * History of significant medical or neurological disorder such as stroke or moderate to severe traumatic brain injury (operationally defined as loss of consciousness for more than 30 minutes) * History of significant or poorly controlled psychiatric disorders * Substantial depression or anxiety affecting their ability to perform tasks necessary for the study. * Current abuse of alcohol or drugs, prescription or otherwise * Nursing a child, pregnant, or intent to become pregnant during the study