Clinical Research Directory

Inclusion Criteria: * Female, aged 18-45 years, right-handed; * Diagnosis of recurrent pregnancy loss-defined as ≥2 consecutive spontaneous miscarriages before 28 weeks' gestation; * Not currently pregnant, or diagnosed with missed abortion at the time of assessment; * Completed structured psychiatric evaluation by licensed psychiatrists at each center, with diagnostic confirmation per DSM-5. Exclusion Criteria: * Use of psychotropic medications in the past month (e.g., SSRIs, SNRIs, TCAs, benzodiazepines, antipsychotics, mood stabilizers); * Unstable or uncontrolled hypertension (SBP \> 180 mmHg or \< 90 mmHg); * Major comorbid organic conditions (e.g., hyperthyroidism, atrial fibrillation, valvular heart disease, stroke, epilepsy, traumatic brain injury, chronic pulmonary disease); * Significant sensory or communication barriers (e.g., hearing impairment, language difficulty, sensory neuropathy) that could impair task performance or stimulus perception; * High suicide risk or severe psychiatric comorbidity (e.g., schizophrenia, bipolar disorder, psychotic disorders, substance use disorders); * Extreme intolerance to auditory, visual, or cold stimuli, based on medical history or pre-test report; * Any other condition judged by the research physician to interfere with participation in the multisensory emotional stimulation protocol.