Clinical Research Directory
Browse clinical research sites, groups, and studies.
Role of Mitochondrial Bioenergetics in Resilience for Gynecologic Cancer
Sponsor: Wake Forest University Health Sciences
Summary
The purpose of this research study is to see if patients with endometrial and ovarian cancer are willing to complete physical and cognitive assessments before treatment and again after treatment has ended.
Official title: The Role of Mitochondrial Bioenergetics in Resilience in Older Adults With Gynecologic Cancer Receiving Cancer Reductive Treatment
Key Details
Gender
FEMALE
Age Range
50 Years - Any
Study Type
OBSERVATIONAL
Enrollment
30
Start Date
2026-06
Completion Date
2027-04
Last Updated
2026-03-03
Healthy Volunteers
No
Conditions
Interventions
muscle sample
For participants undergoing standard of care interval cytoreductive surgery via laparotomy, a skeletal muscle biopsy from the rectus abdominis muscle (1 cm x 1 cm x 1 cm, \~300 mg) will be collected. For participants who undergo standard of care interval cytoreductive surgery with a laparoscopic approach, a skeletal muscle biopsy will be taken from either the rectus abdominis (1 cm x 1 cm x 1 cm, \~300 mg) or the psoas (1 cm x 0.5 cm x 0.5 cm, \~200 mg) muscle.
blood draw
A total of approximately 60mL or 4 tablespoons of blood will be collected throughout the study
Locations (2)
Atrium Health Levine Cancer
Charlotte, North Carolina, United States
Atrium Health Wake Forest Baptist Comprehensive Cancer Center
Winston-Salem, North Carolina, United States