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Ex Vivo Evaluation on Human Tissue of the Binding of Experimental Radiolabeled Ligands
Sponsor: Central Hospital, Nancy, France
Summary
The HERO project aims to structure an ex vivo screening platform, based on anonymized human tissues, to early assess the tissue fixation of experimental ligands in an ethical, translational approach that complies with the principles of the 3Rs (Replacement, Reduction, Refinement).
Official title: Ex Vivo Evaluation of Experimental Radiolabeled Ligand Binding in Human Tissue Using Autohistoradiography HERO (Human Ex-vivo RadiOligand) Platform
Key Details
Gender
All
Age Range
18 Years - 99 Years
Study Type
OBSERVATIONAL
Enrollment
300
Start Date
2025-09-01
Completion Date
2030-09-01
Last Updated
2025-07-18
Healthy Volunteers
No
Conditions
Interventions
Early assessment of tissue uptake of experimental ligands
Ex vivo evaluation of the binding of experimental radiolabeled ligands on human tissue using autohistoradiography