Clinical Research Directory

Inclusion Criteria: 1. Diagnosis : Confirmed autonomic nervous dysfunction (including palmar hyperhidrosis, craniofacial hyperhidrosis, or facial blushing). 2. Age : ≥18 years and ≤55 years. 3. Cardiopulmonary Function : Normal preoperative chest CT scan and electrocardiogram (ECG). 4. Performance Status : ECOG score (see Attachment 1) of 0-1, indicating good clinical fitness and ability to perform daily activities independently. 5. Informed Consent : Patients and their families fully understand the study's purpose, procedures, risks, and potential benefits, voluntarily sign the Informed Consent Form, and agree to participate. Exclusion Criteria: 1\. Abnormal Preoperative ECG : 1. Severe arrhythmias: 1. Type II second-degree or higher atrioventricular block. 2. Symptomatic ventricular arrhythmias. 3. Uncontrolled supraventricular arrhythmias (resting heart rate \>100 bpm). These may cause inadequate cardiac output, hypoperfusion of vital organs, and increased surgical risk. 2. Myocardial ischemia or infarction: 1. ECG showing ST-segment elevation/depression, T-wave inversion. 2. Pathological Q-waves indicating myocardial infarction. 2. Abnormal Chest CT : 1\) Severe pulmonary infections (e.g., lobar pneumonia, empyema) with symptoms like fever, cough, dyspnea. Surgery increases infection risk and may lead to atelectasis or respiratory failure. 2\) Pneumothorax or tension pneumothorax: 1. Significant lung collapse causing dyspnea. 2. Tension pneumothorax requiring immediate chest tube drainage. 3) Pleural effusion (moderate/large volume): Causes dyspnea or mediastinal shift; surgery may worsen respiratory function. 3\. Hyperthyroidism-induced facial blushing or generalized hyperhidrosis. 4. Anesthesia Contraindications : Allergy to anesthetics or high-risk conditions (severe pulmonary/cardiac dysfunction). 5\. Cognitive/Psychiatric Impairment : Inability to provide informed consent or understand study risks. 6\. Non-Compliance with Follow-up : Inability to adhere to postoperative visits. 7\. Immunodeficiency Disorders : Severe immunodeficiency, AIDS, or organ transplant history. 8\. Frailty/Advanced Age : Elderly patients with comorbidities or functional decline unfit for surgery. 9\. Severe Organ Dysfunction : Cirrhosis, renal failure, or inability to tolerate surgery/recovery. 10\. Active Infections : Under antibiotic treatment for pneumonia, tuberculosis, or bacterial infections. 11\. Uncontrolled Diabetes : Poor glycemic control with complications (retinopathy, diabetic foot). 12\. Concurrent Clinical Trials : Participation in other interventional studies affecting results. 13\. Severe Malnutrition : Significant weight loss or nutritional deficiency increasing anesthesia/surgical risks. 14\. Hematologic Disorders : Anemia, thrombocytopenia, or coagulopathies affecting hemostasis/recovery. 15\. Severe Chronic Respiratory Failure : Long-term ventilator dependence or tracheostomy.