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Sarcoma Surgery Wound Complications Comparing Usual Versus Negative Pressure Dressing
Sponsor: NHS Greater Glasgow and Clyde
Summary
To compare the differences in clinical outcomes and health economics between standard absorbent dressings versus Negative Pressure Wound Therapy dressings following the surgical resection of sarcoma tumours.
Official title: Sarcoma Surgery Wound Complications Comparing Usual Versus Negative Pressure Dressing: a Randomised Phase II Trial
Key Details
Gender
All
Age Range
16 Years - Any
Study Type
INTERVENTIONAL
Enrollment
94
Start Date
2025-12-01
Completion Date
2027-09-30
Last Updated
2025-07-09
Healthy Volunteers
No
Interventions
Negative Pressure Wound Therapy (NPWT) Dressings
During wound closure, skin glue is not permitted as this interferes with the NPWT suction mechanism. The NPWT is a mesh-based dressing that will be applied following the transparent occlusive dressing as per the manufacturer's instructions. Patients assigned to NPWT will have their dressing connected to a suction device (ActiV.A.C.®, KCI) providing a constant negative pressure of 125mmHg and left in situ for between 5 and 7 days. The dressings and suction device are all CE-marked medical devices that are being used within their intended usage.
Standard Absorbent Dressings
The wound will be closed as per the standard surgical technique and the operating surgeon's preference. Following wound closure of sarcoma tumour resection, standard absorbent dressing will be applied as per local protocols and the pre-op plan
Locations (1)
Glasgow Royal Infirmary
Glasgow, Scotland, United Kingdom