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ENROLLING BY INVITATION
NCT07049822

Optimising Mammography Screening Accuracy With Blood-based Biomarkers

Sponsor: Vejle Hospital

View on ClinicalTrials.gov

Summary

The project aims to investigate whether breast cancer screening can be improved using blood tests, thereby reducing the number of unnecessary clinical mammographies. The Danish breast cancer screening program was implemented in 2007, and currently, all women aged 50-69 are invited every two years to participate. Those who have a suspecious screening mammography are referred to a clinical mammography where further assesment with more mammographies, ultra-sound and possibly biopsies are conducted. Around 75% of the women that are referred to further assesment can be classified as unnecessary, as no breastcancer is found. This results in avoidable and unpleasant procedures for individuals and strains healthcare resources. The project seeks to reduce the number of these unnecessary clinical mammographies by investigating whether blood biomarkers can identify women at very low risk of breast cancer after a positive mammography screening. By utilizing blood tests, screening could become more personalized, precise, and resource-efficient for the healthcare system.

Official title: OPTIMA: Optimising Mammography Assesment Via Blood-based Biomarkers

Key Details

Gender

FEMALE

Age Range

50 Years - 69 Years

Study Type

OBSERVATIONAL

Enrollment

1200

Start Date

2025-11-24

Completion Date

2029-12-31

Last Updated

2026-03-09

Healthy Volunteers

No

Conditions

Locations (2)

Odense University Hospital

Odense, Denmark

Vejle Hospital

Vejle, Denmark