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Long-term Follow-up Study of Gene Therapy for Arrhythmogenic Cardiomyopathy Due to a Plakophilin-2 Pathogenic Variant
Sponsor: Lexeo Therapeutics
Summary
The primary objective of this Phase 1/2 long-term follow-up (LTFU) study is to assess the long-term safety and tolerability of LX2020 for the treatment of arrhythmogenic cardiomyopathy (ACM) due to a plakophilin-2 gene (PKP2) pathogenic variant (PKP2-ACM).
Official title: A Phase 1/2 Long-term Follow-up Study of the Safety and Efficacy of LX2020 Gene Therapy in Patients With Arrhythmogenic Cardiomyopathy Due to a Plakophilin-2 Pathogenic Variant
Key Details
Gender
All
Age Range
18 Years - 67 Years
Study Type
OBSERVATIONAL
Enrollment
10
Start Date
2025-08-29
Completion Date
2030-08
Last Updated
2025-11-12
Healthy Volunteers
No
Locations (1)
University of Michigan
Ann Arbor, Michigan, United States