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ENROLLING BY INVITATION
NCT07050160

Long-term Follow-up Study of Gene Therapy for Arrhythmogenic Cardiomyopathy Due to a Plakophilin-2 Pathogenic Variant

Sponsor: Lexeo Therapeutics

View on ClinicalTrials.gov

Summary

The primary objective of this Phase 1/2 long-term follow-up (LTFU) study is to assess the long-term safety and tolerability of LX2020 for the treatment of arrhythmogenic cardiomyopathy (ACM) due to a plakophilin-2 gene (PKP2) pathogenic variant (PKP2-ACM).

Official title: A Phase 1/2 Long-term Follow-up Study of the Safety and Efficacy of LX2020 Gene Therapy in Patients With Arrhythmogenic Cardiomyopathy Due to a Plakophilin-2 Pathogenic Variant

Key Details

Gender

All

Age Range

18 Years - 67 Years

Study Type

OBSERVATIONAL

Enrollment

10

Start Date

2025-08-29

Completion Date

2030-08

Last Updated

2025-11-12

Healthy Volunteers

No

Locations (1)

University of Michigan

Ann Arbor, Michigan, United States