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Application of Remimazolam, Dexmedetomidine, and Esketamine in Pediatric Preoperative Sedation
Sponsor: Maternal and Child Health Hospital of Hubei Province
Summary
By comparing the application effects of three drugs in pediatric preoperative sedation, this study explores the optimal medication regimen, aiming to provide safer, more effective, and more personalized medication options for pediatric preoperative sedation. Additionally, this research will also focus on the impact of these three drugs on postoperative agitation in children, offering valuable references for the overall management of pediatric surgical anesthesia.
Official title: A Comparative Study of the Application of Remimazolam, Dexmedetomidine, and Esketamine in Pediatric Preoperative Sedation
Key Details
Gender
All
Age Range
2 Years - 5 Years
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2025-04-01
Completion Date
2026-03-01
Last Updated
2025-07-10
Healthy Volunteers
Yes
Conditions
Interventions
remimazolam group
remimazolam is administered intravenously at a dose of 0.3 mg/kg
dexmedetomidine group
dexmedetomidine is administered intravenously at a dose of 1 μg/kg
esketamine group
esketamine is administered intravenously at a dose of 0.5 mg/kg
Locations (1)
Maternal and Child Health Hospital of Hubei Province
Wuhan, Hubei, China