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Postbiotics for Mitigation of Postoperative Dysbiosis in Gastrointestinal Cancer Surgery
Sponsor: University of South Florida
Summary
To measure the efficacy of postbiotic supplements in mitigating the gut dysbiosis induced by colon cancer surgery. Efficacy in mitigating dysbiosis will be measured by the change in fecal Shannon Diversity Index (SDI) within patients from the baseline sample to various postoperative timepoints. Mean change in SDI from baseline will be compared between groups at 2 weeks postoperative
Official title: Postbiotics for Mitigation of Postoperative Dysbiosis in Gastrointestinal Cancer Surgery: A Randomized, Single-blinded, Placebo-controlled Trial (REPOT)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2025-07-15
Completion Date
2026-12-30
Last Updated
2025-12-29
Healthy Volunteers
No
Conditions
Interventions
PoZibio
1 gummy once daily
Inert placebo
1 gummy once daily
Locations (2)
Tampa General Hospital
Tampa, Florida, United States
University of South Florida
Tampa, Florida, United States