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ENROLLING BY INVITATION
NCT07050485
NA

Postbiotics for Mitigation of Postoperative Dysbiosis in Gastrointestinal Cancer Surgery

Sponsor: University of South Florida

View on ClinicalTrials.gov

Summary

To measure the efficacy of postbiotic supplements in mitigating the gut dysbiosis induced by colon cancer surgery. Efficacy in mitigating dysbiosis will be measured by the change in fecal Shannon Diversity Index (SDI) within patients from the baseline sample to various postoperative timepoints. Mean change in SDI from baseline will be compared between groups at 2 weeks postoperative

Official title: Postbiotics for Mitigation of Postoperative Dysbiosis in Gastrointestinal Cancer Surgery: A Randomized, Single-blinded, Placebo-controlled Trial (REPOT)

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2025-07-15

Completion Date

2026-12-30

Last Updated

2025-12-29

Healthy Volunteers

No

Interventions

DIETARY_SUPPLEMENT

PoZibio

1 gummy once daily

DIETARY_SUPPLEMENT

Inert placebo

1 gummy once daily

Locations (2)

Tampa General Hospital

Tampa, Florida, United States

University of South Florida

Tampa, Florida, United States