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Effect of Inulin Supplementation on Glycaemic Control and Immunological Parameters in Type 1 Diabetes (2024)
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Summary
The goal is to establish the effect of oral inulin supplementation on continuous glucose monitoring (CGM) metrics and immunological parameters in adults with type 1 diabetes. The investigators will perform a double-blind, randomized, placebo-controlled trial in 2x38 participants to measure effects on CGM metrics, gut microbiome composition, residual beta cell and immunological parameters.
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
76
Start Date
2025-05-09
Completion Date
2027-04
Last Updated
2025-07-03
Healthy Volunteers
No
Conditions
Interventions
Inulin (prebiotic, fermentable fiber)
inulin (prebiotic, fermentable fiber)
Placebo
placebo (matodextrin)
Locations (2)
Diabeter Centrum Amsterdam
Amsterdam, Netherlands
Amsterdam UMC
Amsterdam, Netherlands