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Transcutaneous Auricular Vagus Nerve Stimulation as Adjuvant Treatment for Sepsis Patients
Sponsor: Third Military Medical University
Summary
The goals of this randomized clinical trial are to investigate the effects of transcutaneous auricular vagus nerve stimulation (taVNS) combined with standard intensive care on systemic organ function in septic patients, and exploring its potential mechanisms for improving overall outcomes in sepsis.The main question it aims to answer is whether taVNS can reduce the severity of sepsis patients by ameliorating systemic inflammation.Participants will receive standard intensive care treatment and be randomized to receive the taVNS or sham taVNS as adjuvant treatment twice a day for 7 consecutive days. Several evaluations will be done before and after the intervention.
Official title: Exploratory Study on Transcutaneous Auricular Vagus Nerve Stimulation as Adjuvant Treatment for Sepsis Patients
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2025-02-27
Completion Date
2026-12-31
Last Updated
2025-07-04
Healthy Volunteers
No
Conditions
Interventions
taVNS
Transcutaneous Auricular Vagus Nerve Stimulation
sham-taVNS
sham transcutaneous auricular vagus nerve stimulation
Locations (1)
The First Affiliated Hospital of Army Medical University
Chongqing, China