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RECRUITING
NCT07051694
NA

Transcutaneous Auricular Vagus Nerve Stimulation as Adjuvant Treatment for Sepsis Patients

Sponsor: Third Military Medical University

View on ClinicalTrials.gov

Summary

The goals of this randomized clinical trial are to investigate the effects of transcutaneous auricular vagus nerve stimulation (taVNS) combined with standard intensive care on systemic organ function in septic patients, and exploring its potential mechanisms for improving overall outcomes in sepsis.The main question it aims to answer is whether taVNS can reduce the severity of sepsis patients by ameliorating systemic inflammation.Participants will receive standard intensive care treatment and be randomized to receive the taVNS or sham taVNS as adjuvant treatment twice a day for 7 consecutive days. Several evaluations will be done before and after the intervention.

Official title: Exploratory Study on Transcutaneous Auricular Vagus Nerve Stimulation as Adjuvant Treatment for Sepsis Patients

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2025-02-27

Completion Date

2026-12-31

Last Updated

2025-07-04

Healthy Volunteers

No

Conditions

Interventions

DEVICE

taVNS

Transcutaneous Auricular Vagus Nerve Stimulation

DEVICE

sham-taVNS

sham transcutaneous auricular vagus nerve stimulation

Locations (1)

The First Affiliated Hospital of Army Medical University

Chongqing, China