Clinical Research Directory
Browse clinical research sites, groups, and studies.
Comparative Evaluation of Hydrophilic and Hydrophobic Sealants in Partially Erupted First Molars
Sponsor: Mansoura University
Summary
This randomized controlled clinical trial aims to evaluate and compare the retention, caries prevention, microleakage, and fluoride release of three types of pit and fissure sealants-hydrophilic, nanofilled hydrophobic, and conventional hydrophobic-applied to partially erupted first permanent molars in children aged 5 to 7 years. The study uses a split-mouth design and includes both clinical and laboratory evaluations over an 18-month period. Outcomes will assess sealant effectiveness with and without the use of a bonding agent.
Official title: Evaluation of Hydrophilic and Hydrophobic Sealants' Retention, Caries Prevention, Microleakage, and Fluoride Release in Partially Erupted First Permanent Molars:A Randomized Controlled Clinical Trial
Key Details
Gender
All
Age Range
5 Years - 7 Years
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2025-07-01
Completion Date
2027-04-01
Last Updated
2025-07-09
Healthy Volunteers
Yes
Conditions
Interventions
Prevention
Conventional Hydrophobic Sealant (Helioseal F - Control) will be used as a positive control; applied to partially erupted molars with and without bonding in a split-mouth design.
Prevention of caries
Embrace WetBond sealant will be applied to partially erupted first permanent molars using a split-mouth design with and without bonding agent.
Prevention therapy
DENU Seal applied using a split-mouth design to evaluate bonding and non-bonding application outcomes from retention and caries prevention
Locations (1)
Facility of Dentistry،Mansoura University
Al Mansurah, Egypt