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The Characteristics and Treatment Mechanism of Vascular Grafts in Elderly Patients With CAOD Through Single-cell Transcriptome Analysis
Sponsor: Yonsei University
Summary
This study aims to establish a cardiovascular biobank using vascular grafts obtained from participants with coronary artery occlusive disease (CAOD). Through genomic and transcriptomic analyses, the study seeks to characterize the biological features of the vascular grafts and identify potential therapeutic targets and mechanisms related to vascular remodeling and stiffness.
Key Details
Gender
All
Age Range
19 Years - 100 Years
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2022-04-12
Completion Date
2027-04-11
Last Updated
2025-07-08
Healthy Volunteers
No
Conditions
Locations (1)
Division of Cardiovascular Surgery, Severance Cardiovascular Hospital , Yonsei University College of Medicine
Seoul, South Korea