Clinical Research Directory
Browse clinical research sites, groups, and studies.
Endarterectomy Versus Stenting in Patients With Symptomatic Severe Carotid Stenosis - 2
Sponsor: Centre Hospitalier St Anne
Summary
Carotid stenosis caused by atherosclerosis is a significant risk factor for ischemic stroke, accounting for up to 15% of all strokes and transient ischemic attacks. Randomized clinical trials (RCTs) have demonstrated the benefits of carotid endarterectomy (CEA) in reducing stroke risk in patients with severe symptomatic carotid stenosis. Carotid artery stenting (CAS) has been developed as an alternative to CEA, offering several potential advantages, such as avoiding local surgical complications. However, unlike CEA, CAS has not been compared to medical therapy in RCTs for symptomatic carotid stenosis.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
600
Start Date
2025-07-16
Completion Date
2028-03-16
Last Updated
2025-07-24
Healthy Volunteers
No
Conditions
Interventions
carotid endarterectomy
Carotid endarterectomy is a surgical procedure used to reduce the risk of stroke due to carotid artery stenosis. During an endarterectomy, the surgeon opens the artery and removes the plaque.
Carotid artery stenting
Carotid artery stenting is an endovascular procedure in which a stent is deployed in the lumen of the carotid artery to treat narrowing of the carotid artery and reduce the risk of stroke.
Locations (1)
Centre hospitalier Sainte-Anne
Paris, France