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Assessment of Serum Catestatin Level in Acne Vulgaris Patients
Sponsor: Aswan University
Summary
Acne vulgaris is a persistent inflammatory condition of the pilosebaceous unit, affecting 85% of people between the ages of 12 and 24, it is regarded as one of the most common diseases in teenagers and young adults. Catestatin, a peptide derived from chromogranin A (CgA), was first discovered in 1997 as an acute nicotinic-cholinergic antagonist. Later, it was determined that CST is a pleiotropic hormone.
Official title: Assessment of Serum Catestatin Level in Acne Vulgaris Patients Before and After Treatment With Oral Isotretinoin
Key Details
Gender
All
Age Range
18 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2025-01-10
Completion Date
2026-01-10
Last Updated
2025-07-08
Healthy Volunteers
Yes
Conditions
Interventions
Isotretinoin
* Measure the serum levels of catestatin in patients with moderate and severe acne vulgaris versus healthy control persons. * Evaluate the effect of oral isotretinoin treatment on serum catestatin levels in patients with moderate and severe acne vulgaris.
Locations (1)
Aswan Unuversity Hospital
Aswān, Egypt