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Repetitive Transcranial Magnetic Stimulation Combined With Bimanual Therapy for Upper Limb Stroke Rehabilitation
Sponsor: Chang Gung Memorial Hospital
Summary
The goal of this clinical trial is to evaluate whether combining repetitive transcranial magnetic stimulation (rTMS) with machine-assisted bimanual therapy (BT) can improve upper limb function in stroke patients. The participants will be individuals aged 40-80 years who have experienced a first-time ischemic or hemorrhagic stroke. The main questions it aims to answer are: * Does the combined therapy enhance motor recovery compared to traditional rehabilitation methods? * Are changes in brain activity associated with improvements in upper limb function? Participants will be randomly assigned to different groups and will: * Receive rTMS stimulation on specific areas of the brain to modulate neural activity, * Perform machine-assisted bimanual exercises to promote motor skills, and * Undergo assessments before, immediately after, and during follow-up periods to measure functional improvements.
Official title: Development of Repetitive Transcranial Magnetic Stimulation (rTMS) Combined With Machine-assisted Bimanual Therapy (BT) in Upper Limb Rehabilitation
Key Details
Gender
All
Age Range
40 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
54
Start Date
2025-07-15
Completion Date
2027-07-31
Last Updated
2025-07-08
Healthy Volunteers
No
Conditions
Interventions
Conventional occupation therapy
Standard occupational therapy focused on improving daily functional skills through task-specific training and adaptive techniques.
stretching exercise
Techniques involving passive or active stretching of muscles to enhance flexibility, reduce spasticity, and prevent contractures.
rTMS
Non-invasive brain stimulation method using magnetic pulses to modulate cortical excitability and promote neural plasticity.
bimanual therapy
A training approach that involves simultaneous use of both hands to enhance coordination and functional hand movements through guided exercises, including device-assisted and robot-assisted therapy
Locations (1)
Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital at Linkou, Taoyuan 333, Taiwan
Taoyuan District, Taiwan