Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
RECRUITING
NCT07054489
NA

UPBEAT: Using Polygenic Scores to Guide BB Therapy in HF With Mildly Reduced EF

Sponsor: David Lanfear

View on ClinicalTrials.gov

Summary

This study will use polygenic scores, a tool which describes differences in genetics, to examine effectiveness of beta blocker medication in heart failure patients with ejection fraction of 41-50 percent. The study will also assess beta blockers' effect on the changes in left ventricular end-systolic volume index by MRI.

Official title: Using Polygenic Scores to Guide Beta-blocker Therapy for Heart Failure With Mildly Reduced Ejection Fraction

Key Details

Gender

All

Age Range

18 Years - 89 Years

Study Type

INTERVENTIONAL

Enrollment

10

Start Date

2025-11

Completion Date

2026-11

Last Updated

2025-11-10

Healthy Volunteers

No

Interventions

OTHER

Beta blocker

Participants randomized to intervention will be dosed and titrated on beta blocker according to study protocol.

Locations (1)

Henry Ford Health

Detroit, Michigan, United States