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Optimal Meals to Reduce Bone Resorption in Women With Osteopenia
Sponsor: University of Aarhus
Summary
The goal of this clinical trial is to investigate whether different types of small meals can help reduce bone loss in postmenopausal women with osteopenia, a condition where bone density is lower than normal and may lead to osteoporosis. The main hypothesis is: \- A small amount of dairy (100 ml) is just as effective as a larger meal containing dairy and banana in reducing bone resorption. Based on this, the study aims to answer the following questions: \- Which type and size of meal is most effective in reducing bone resorption? Researchers will compare five different types of meals to a fasting control day to determine which meals best reduce markers of bone loss in the blood. Participants will attend six clinical visits: five involving the intake of different test meals, and one control visit involving fasting. The participants will have blood samples taken over a period of 6 hours after each meal or fasting period to measure markers of bone metabolism. This study aims to identify a simple, non-drug-based strategy to support bone health and help prevent progression to osteoporosis.
Key Details
Gender
FEMALE
Age Range
Any - 80 Years
Study Type
INTERVENTIONAL
Enrollment
13
Start Date
2025-10
Completion Date
2026-05
Last Updated
2025-07-09
Healthy Volunteers
No
Conditions
Interventions
200 ml dairy
Participants consume the meal after a fasting baseline bloodsample. Bloodsamples are collected over a six-hour period to evaluate postpandrial changes in bone turnover markers.
100 ml milk
Participants consume the meal after a fasting baseline bloodsample. Bloodsamples are collected over a six-hour period to evaluate postpandrial changes in bone turnover markers.
100 g banana
Participants consume the meal after a fasting baseline bloodsample. Bloodsamples are collected over a six-hour period to evaluate postpandrial changes in bone turnover markers.
100 ml dairy and fibers
Participants consume the meal after a fasting baseline bloodsample. Bloodsamples are collected over a six-hour period to evaluate postpandrial changes in bone turnover markers.
Fasting (control)
Participants consume the meal after a fasting baseline bloodsample. Bloodsamples are collected over a six-hour period to evaluate postpandrial changes in bone turnover markers.
100 ml dairy
Participants consume the meal after a fasting baseline bloodsample. Bloodsamples are collected over a six-hour period to evaluate postpandrial changes in bone turnover markers.
Locations (1)
Department of Endocrinology and Internal Medicine, Aarhus University Hospital
Aarhus N, Denmark