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Long-term Brain Stimulation of the Motor Ventral Thalamus (VOP/VIM) to Improve Motor Function
Sponsor: Jorge Gonzalez-Martinez
Summary
This study aims to recruit patients already implanted with Deep Brain Stimulation (DBS) for movement disorders to complete tasks assessing parameters of motor output, speech, and swallowing functions, both with and without stimulation. DBS parameters would be adjusted prior to motor testing. Patients would then participate in multiple sessions performing contralateral upper extremity movement tasks measuring movement speed, grip strength, and strength modulation, facial movement, swallowing, and speech tasks.
Official title: Chronic Stimulation of the Motor Ventral Thalamus (VOP/VIM) for Motor Control in Humans
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2022-05-10
Completion Date
2030-12-31
Last Updated
2025-12-16
Healthy Volunteers
Yes
Conditions
Interventions
Deep Brain Stimulation (DBS) of the Motor Thalamus
All participants enrolled will undergo stimulation parameters tuning of deep brain stimulation electrode leads. All subjects will participate in a series of experiments to evaluate the stimulation effects on movement of face and upper extremities, swallowing, and speech abilities.
Locations (1)
University of Pittsburgh
Pittsburgh, Pennsylvania, United States