Clinical Research Directory

Inclusion Criteria: * Patients or family gave written informed consents to participate in this study. * Patients with first hemiplegia caused by primary supratentorial intracerebral hemorrhage or cerebral infarction. * Within 1 year of stroke onset * Aged ≥ 20 * Body weight is between 40 and 80 kg * No excessive spasticity in hip, knee, and ankle joints (Modified Ashworth Scale \<3) * sufficient cognition to follow simple instructions and to understand the content and purpose of the study (Chinese version-MOCA ≥ 20 points) * Patients who have risks of giving-way when they walk with Ankle-Foot orthosis (AFO) Exclusion Criteria: * A history of myocardial infarction * Muscular or neurological disorder including diabetic neuropathy * Symptomatic angina or arrhythmia * Symptomatic respiratory disorder * Communicable infection * Joint contracture or limb deformity that affects walking (Range of motion of hip extension \< 5 degree, knee extension \< -5 degree (can be flexible), ankle dorsiflexion with knee extension position \< 5 degree) * Heterotropic ossification that restrict the range of motion of joints of lower extremities * Being vulnerable to fracture like severe osteoporosis of spine or lower extremities * Incontinence of urine or feces that may deface the robotic knee-ankle-foot device of Welwalk * Inadequate control of hypertension (resting systolic blood pressure ≥ 180 mmHg or diastolic blood pressure ≥ 120 mmHg) * Inadequate control of tachycardia (heart rate at rest ≥ 120 bpm) * Training restriction due to reduced cardiac function or respiratory dysfunction * Visual or auditory impairment hindering training * Pregnant patients * Recent participation in other clinical trials * Patient whom examination doctor judge improper as a trial subject * Anyone not able to sustain the training protocol with Welwork or regular training