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Acute Effects of Powdered Beetroot Extract Supplementation on the Microcirculation of Resistant Hypertensive Individuals
Sponsor: National Institute of Cardiology, Laranjeiras, Brazil
Summary
Arterial hypertension is a major public health issue and is considered to be a new epidemic due to its high mortality and morbidity rates. Elevated blood pressure levels increase the risk of coronary artery disease, heart failure, stroke, chronic kidney disease and death. Dietary nitrate supplementation in the form of beetroot powder extract may offer a more accessible way to increase systemic nitric oxide availability and consequently promote vasodilation in these patients. However, studies are needed to assess its benefits in patients with hypertension.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2024-06-01
Completion Date
2026-12
Last Updated
2025-07-23
Healthy Volunteers
No
Conditions
Interventions
evaluation of systemic microvascular reactivity
Evaluation of systemic microvascular reactivity using laser speckle contrast imaging.
ABPM
Ambulatory blood pressure measuring: systolic, diastolic and mean arterial pressures
beetroot supplement
A powdered beetroot extract supplement containing 400 mg of nitrate per dose will be used in the supplement group, administered orally at a daily amount of 10 g.
Locations (1)
National Institute of Cardiology
Rio de Janeiro, Rio de Janeiro, Brazil