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Atrioventricular Nodal Ablation Versus Pulmonary Vein Isolation - Patient Centred Decisions
Sponsor: Sunshine Coast Hospital and Health Service
Summary
The goal of this clinical trial is to compare two procedural approaches to managing atrial fibrillation. The main questions it aims to answer are: Is AF ablation or pacemaker implant and AV nodal ablation a more effective treatment approach for patients with atrial fibrillation refractory to pharmacological treatment? What effect do these differing treatment approaches have on patient's quality of life and mental health? Participants will: Be randomly allocated to one of the treatment approaches. Visit the clinic 2 months, 12 months and 24 months after their procedure for a checkup, questionnaires and repeat heart ultrasounds.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
172
Start Date
2025-09
Completion Date
2031-09
Last Updated
2025-07-14
Healthy Volunteers
No
Conditions
Interventions
Atrioventricular nodal ablation
Patients randomised to this arm would undergo physiological pacing followed by atrioventricular nodal ablation
Pulmonary vein isolation
Patients randomised to this arm would undergo catheter ablation targeted at achieving pulmonary vein isolation