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Cognitive Processing Therapy (CPT) for Perinatal Posttraumatic Stress Disorder (PTSD)
Sponsor: University of Texas at Austin
Summary
Pregnant women with a primary diagnosis of posttraumatic stress disorder (PTSD) (PTSD Checklist for DSM-5 (PCL-5) score \> 33) will be randomized to receive conventional cognitive processing therapy (CPT) (60-min session once/week for 12 weeks) or massed CPT (mCPT) (an intensive schedule of 12 60-min sessions over 5 days, approximately 2-3 sessions per day) via telemedicine, for treatment of PTSD. The research aims will be three-fold: (1) Evaluate the relative efficacy and tolerability of CPT vs. mCPT for treatment of perinatal PTSD and depression; (2) Determine the effect of CPT upon maternal-infant attachment and interaction; (3) Collect pilot data of obstetric and neonatal outcomes among those receiving the two CPT delivery schedules.
Key Details
Gender
FEMALE
Age Range
18 Years - 46 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2025-07
Completion Date
2026-12
Last Updated
2025-07-11
Healthy Volunteers
No
Interventions
Regular CPT
Standard-model Cognitive Processing Therapy (CPT) - one 60-min session per week for 12 weeks total
Massed CPT
Massed CPT - two 60-min sessions each day for 5 consecutive days (10 sessions total)
Locations (1)
University of Texas at Austin, Dell Medical School, Department of Psychiatry
Austin, Texas, United States