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ENROLLING BY INVITATION
NCT07060625

The Effect of Semi-recumbent Position on Hypoxemia After Lung Segment/Lobe Surgery

Sponsor: Shanghai Pulmonary Hospital, Shanghai, China

View on ClinicalTrials.gov

Summary

Thoracoscopic surgery is the most common surgical approach in thoracic surgery, which reduces surgical trauma and postoperative pain compared with open thoracotomy, but postoperative complications should not be overlooked, with hypoxemia being particularly prominent. Postoperative hypoxemia is highly prevalent among patients recovering from non-cardiac surgery, accounting for over one-third of all cases. Hypoxemia impairs wound healing and leads to other severe complications such as cerebral dysfunction, arrhythmia, and myocardial ischemia, all of which adversely affect postoperative recovery. Although oxygen therapy can prevent and treat hypoxemia, many patients still experience hypoxia in the post-anesthesia care unit (PACU). Numerous studies have investigated various ventilation techniques aimed at enhancing postoperative pulmonary function, but the benefits of protective ventilation strategies may be lost during emergence from anesthesia. Several other studies also indicate that intraoperative ventilation measures do not improve postoperative pulmonary function. The lack of evidence demonstrating the efficacy of oxygen therapy or protective ventilation techniques in treating postoperative hypoxemia underscores the need to explore alternative strategies. Patient positioning during emergence from anesthesia is associated with perioperative and postoperative complications. Although no consensus exists on the optimal patient position during emergence, the supine position is often favored by anesthesiologists due to its simplicity and ease of monitoring. However, the reduced functional residual capacity associated with the supine position tends to promote airway closure and diminish gas exchange.

Official title: The Effect of Semi-recumbent Position on Hypoxemia During the Recovery Period of General Anesthesia After Lung Segment/Lobe Surgery: a Single Center, Prospective, Real-world Study

Key Details

Gender

All

Age Range

18 Years - 85 Years

Study Type

OBSERVATIONAL

Enrollment

308

Start Date

2024-12-23

Completion Date

2026-09-30

Last Updated

2025-07-11

Healthy Volunteers

No

Interventions

BEHAVIORAL

Semi-reclining position

During anesthesia recovery, the patient's position should be in a semi-recumbent position

Locations (1)

Shanghai Pulmonary Hospital

Shanghai, Shanghai Municipality, China