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Comparative Effects of Exercise and Metformin on Glycemic Control in Prediabetic Adults
Sponsor: Umair Ali
Summary
This study is being done to compare the effect of regular exercise and metformin in people who have prediabetes. It is a community-based, open-label, randomized trial in which eligible participants will be divided into two groups. One group will do moderate physical exercise, and the other group will take metformin for 12 weeks. We will check their fasting blood sugar and HbA1c before and after the treatment to see which method works better for controlling sugar levels. The study is being done in a low-resource community setup to see which option is more practical and effective in real-life Pakistani settings.
Official title: Comparative Effects of Exercise and Metformin on Glycemic Control in Prediabetic Adults: A Community-Based, Open-Label, Randomized Trial in a Low-Resource Setting
Key Details
Gender
All
Age Range
18 Years - 59 Years
Study Type
INTERVENTIONAL
Enrollment
226
Start Date
2025-08-10
Completion Date
2026-03-15
Last Updated
2025-07-23
Healthy Volunteers
No
Conditions
Interventions
Moderately intense exercise
Structured moderate-intensity aerobic activity (e.g., brisk walking) for 30-45 minutes/day, 5 days/week, for 12 weeks.
MetFORMIN 500 Mg Oral Tablet
Participants will receive oral metformin 500 mg twice daily for 12 weeks.
Locations (1)
Department of Preventive Medicine, Combined Military Hospital Nowshera
Nowshera, Pakistan