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RECRUITING
NCT07061678
PHASE4

The Effect of Dexamethasone Administration Route in Pediatric Brachial Plexus Block

Sponsor: Poznan University of Medical Sciences

View on ClinicalTrials.gov

Summary

This study aims to assess the impact of the administration route of dexamethasone (intravenous vs. perineural) on postoperative pain and inflammatory response in pediatric patients undergoing hip surgery. The primary outcome is postoperative pain intensity measured using an age-appropriate scale at multiple intervals. Secondary outcomes include inflammatory markers such as neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR), opioid consumption, time-to-first rescue analgesia, and overall patient recovery. This randomized, double-blinded study seeks to improve pain management strategies and optimize anesthesia protocols in pediatric arm surgery.

Official title: The Effect of Dexamethasone Administration Route in Infraclavicular Brachial Plexus Block for Pediatric Arm and/or Hand Surgery

Key Details

Gender

All

Age Range

3 Months - 6 Years

Study Type

INTERVENTIONAL

Enrollment

90

Start Date

2025-10-01

Completion Date

2026-02-28

Last Updated

2025-11-25

Healthy Volunteers

No

Conditions

Interventions

DRUG

perineural dexamethasone

infraclavicular brachial plexus block with 0.2ml/kg 0.2% ropivacaine with 0.1mg/kg perineural dexamethasone

DRUG

intravenous dexamethasone

infraclavicular brachial plexus block with 0.2ml/kg 0.2% ropivacaine with 0.1mg/kg intravenous dexamethasone

DRUG

0.2ml/kg 0.2% ropivacaine

infraclavicular brachial plexus block with 0.2ml/kg 0.2% ropivacaine

Locations (2)

Poznan University of Medical Sciences

Poznan, Poland

Poznan University of Medical Sciences

Poznan, Poland